Phone: 1-617-432-6543

Email: mcolaiacovo@genetics.med.harvard.edu

Publications

2017

Regulation of Crossover Frequency and Distribution during Meiotic Recombination.

Saito TT and Colaiacovo MP.
Cold Spring Harb Symp Quant Biol. 2017 Dec 8. pii: 034132. doi: 10.1101/sqb.2017.82.034132.

Wrestling with Chromosomes: The Roles of SUMO During Meiosis.

Nottke AC, Kim HM, Colaiácovo MP.
Adv Exp Med Biol. 2017;963:185-196. doi: 10.1007/978-3-319-50044-7_11. Review

Polo-like kinase-dependent phosphorylation of the synaptonemal complex protein SYP-4 regulates double-strand break formation through a negative feedback loop.

Nadarajan S, Lambert TJ, Altendorfer E, Gao J, Blower MD, Waters JC, Colaiácovo MP
Elife. 2017 Mar 27;6. pii: e23437

2016

N-terminal acetylation promotes synaptonemal complex assembly in C. elegans.

Gao J, Barroso C, Zhang P, Kim HM, Li S, Labrador L, Lightfoot J, Gerashchenko MV, Labunskyy VM, Dong MQ, Martinez-Perez E, Colaiácovo MP.
Genes Dev. 2016 Nov 1;30(21):2404-2416. Epub 2016 Nov 14.

The MAP kinase pathway coordinates crossover designation with disassembly of synaptonemal complex proteins during meiosis.

Nadarajan S, Mohideen F, Tzur YB, Ferrandiz N, Crawley O, Montoya A, Faull P, Snijders AP, Cutillas PR, Jambhekar A, Blower MD, Martinez-Perez E, Harper JW and Colaiacovo MP
Elife. 2016 Feb 27;5. pii: e12039.

CRISPR-Cas9-guided Genome Engineering in C. elegans.

Kim HM and Colaiácovo MP
Current Protocols in Molecular Biology. Wiley Online Library.

2015

Efficient Genome Editing in Caenorhabditis elegans with a Toolkit of Dual-Marker Selection Cassettes.

Norris AD, Kim HM, Colaiácovo MP, Calarco JA.
Genetics. 2015 Oct;201(2):449-58. doi: 10.1534/genetics.115.180679. Epub 2015 Jul 30.

DNA damage sensitivity assays in Caenorhabditis elegans.

Kim HM and Colaiácovo MP
Bio-protocol 5(11): e1487

New Insights into the Post-Translational Regulation of DNA Damage Response and Double-Strand Break Repair in Caenorhabditis elegans

Kim HM and Colaiácovo MP
Genetics. 115.175661; Early online 2015 March 26,doi:10.1534/genetics.115.175661.

NatB Domain-Containing CRA-1 Antagonizes Hydrolase ACER-1 Linking Acetyl-CoA Metabolism to the Initiation of Recombination during C. elegans Meiosis.

Gao, J., Kim, H.M., Elia A.E., Elledge, S.J., and Colaiácovo, M.P.
PLoS Genetics. 11(3): e1005029.

Investigating the Role of RIO Protein Kinases in Caenorhabditis elegans

Mendes TK, Novakovic S, Raymant G, Bertram SE, Esmaillie R, Nadarajan S, Breugelmans B, Hofmann A, Gasser RB, Colaiácovo MP, Boag PR.
PLoS One. 10(2):e0117444.

Contact Details

Dr. Monica Colaiacovo
Blavatnik Institute, Harvard Medical School
Department of Genetics 
New Research Building, Room 334 
77 Avenue Louis Pasteur, Boston, MA 02115 USA 
Telephone: 1-617-432-6543
Email: mcolaiacovo@genetics.med.harvard.edu