YITZHAK PILPEL
Peer-Reviewed Articles
14. Sudarsanam P*, Pilpel Y*, Church G. Genome-wide co-occurrence of promoter elements reveals a cis-regulatory cassette of rRNA transcription motifs in S. cerevisiae Genome Rsearch 12, 1723-1731 (2002). . *these authors have equal contribution to the work
13. Zhu Z*, Pilpel, Y*. & Church G. Identification of transcription factor binding sites via a Transcription Factor-Centric Clustering (TFCC) algorithm. J.Mol.Biol. 318, 71-81 (2002). *these authors have equal contribution to the work
12. Cohen, B., Pilpel, Y., Mitra, R. & Church, G. Discrimination between the Yap1p and Yap2p transcriptional networks in yeast. Mol. Biol. Cell. 13 (2002).
11. Pilpel, Y*., Sudarsanam, P*. & Church, G. Identifying regulatory networks by combinatorial analysis of promoter elements. Nature Genetics 29 153-159 (2001). *these authors have equal contribution to the work
10. Fuchs, T., Glusman, G., Horn-Saban, S., Lancet, D. & Pilpel, Y. The human olfactory subgenome: from sequence to structure and evolution. Hum Genet 108, 1-13 (2001).
9. Lapidot, M., Pilpel, Y., Gilad, Y., Falcovitz, A., Sharon, D., Haaf, T. & Lancet, D. Mouse-Human Orthology Relationships in an Olfactory Receptor Gene Cluster. Genomics 71, 296-306 (2001).
8. Conticello, S.G., Pilpel, Y., Glusman, G. & Fainzilber, M. Position-specific codon conservation in hypervariable gene families. Trends Genet 16, 57-59 (2000).
7. Glusman, G., Bahar, A., Sharon, D., Pilpel, Y., White, J. & Lancet, D. The olfactory receptor gene superfamily: data mining, classification, and nomenclature. Mamm Genome 11, 1016-1023 (2000).
6. Pilpel, Y., Ben-Tal, N. & Lancet, D. kPROT: a knowledge-based scale for the propensity of residue orientation in transmembrane segments. Application to membrane protein structure prediction. J Mol Biol 294, 921-935 (1999).
5. Sharon, D., Glusman, G., Pilpel, Y., Khen, M., Gruetzner, F., Haaf, T. & Lancet, D. Primate evolution of an olfactory receptor cluster: diversification by gene conversion and recent emergence of pseudogenes. Genomics 61, 24-36 (1999).
4. Pilpel, Y. & Lancet, D. The variable and conserved interfaces of modeled olfactory receptor proteins. Protein Sci 8, 969-977 (1999).
3. Segre, D., Lancet, D., Kedem, O. & Pilpel, Y. Graded autocatalysis replication domain (GARD): kinetic analysis of self-replication in mutually catalytic sets. Orig Life Evol Biosph 28, 501-514 (1998).
2. Segre, D., Pilpel, Y. & Lancet, D. Mutual catalysis in sets of prebiotic organic molecules: Evolution through computer simulated chemical kinetics. PhysicaA 249, 558-564 (1998).
1. Lancet, D., Kedem, O. & Pilpel, Y. Emergence of order in small autocatalytic sets mantained far from equilibrium: application of a probabilistic receptor affinity distribution (RAD) model. Ber Bunsenges Phys Chem 98, 1166-1169 (1994).
Reviews
2. Pilpel, Y. & Lancet, D. Olfaction. Good reception in fruitfly antennae. Nature 398, 285-287 (1999).
1. Sharon, D., Glusman, G., Pilpel, Y., Horn-Saban, S. & Lancet, D. Genome dynamics, evolution, and protein modeling in the olfactory receptor gene superfamily. Ann N Y Acad Sci 855, 182-193 (1998).
Book Chapters and conference proceedings
2. Pilpel, Y., Sosinsky, A. & Lancet, D. Molecular biology of olfactory receptors. Essays Biochem 33, 93-104 (1998).
1. Segré, D. Pilpel, Y. Glusman, G. & Lancet, D. Self-Replication and Evolution in Primordial Mutually Catalytic Sets, in: C. B. Cosmovici, S. Bowyer, D. Werthimer, Astronomical and Biochemical Origins and the Search for Life in the Universe (Editrice Compositori, Bologna, 1997) 469-476. (1997).
Industry Reports
14. Pilpel Y. Identification of ligand-binding sites in GPCRs from high throughput binding screening data: application of a Recursive Partitioning algorithm. Pfizer Discovery Technology Center, internal report.
Abstracts
5. Pilpel, Y., Sudarsanam, P. & Church, G. Identifying regulatory networks by combinatorial analysis of promoter elements. Proceedings of ISMB2001 (2001).
4. Pilpel, Y., Sudarsanam, P. & Church, G. Whole-Genome analysis of Combinatorial Regulation of Gene Networks. Proceedings of ISMB2000 (2000).
3. Pilpel, Y., Lancet, D. & Ben-Tal, N. On structure prediction in membrane proteins using a set of sequence-derived membranophobicity scales. Biophys. J 76, (1999).
2. Pilpel, Y., Segré, D., Lancet, D., Weissinger, Y. & Glusman, G. Multiple Sequence Analysis of Olfactory Receptor Genes: Sequence, Structure and Function Relationships. Folding & Design 51-52 (1996).
1. Lancet, D., Glusman, G., Segrè, D., Kedem, O. & Pilpel, Y. Self-replication and chemical selection in primordial mutually catalytic sets. Orig Life Evol Biosp 26, 270-271 (1996).