CURRICULUM VITAE

YITZHAK PILPEL

June 24, 2002

Born: September 12, 1968, Jerusalem, Israel.

Current Position: Post-doctoral Research Fellow at the Department of Genetics and Lipper center for Computational Genetics, Harvard Medical School.

Address: 200 Longwood Avenue, Boston, MA 02115 USA.

Fax: 617-432-7266

Phone: 617-432-4125

Email: tpilpel@genetics.med.harvard.edu

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EDUCATION

1982-1986 Special enriched program, including courses in biology and mathematics, for gifted high school students at the Ben-Gurion University, Beer-Sheva.

1990-1993 B.Sc. in Biology at the Tel Aviv University.

1993-1994 Studies towards M.Sc. at the Feinberg Graduate School of the Weizmann Institute of Science. Transferred to the direct path to Ph.D.

1995-1999 Ph.D. studies with distinction at the Weizmann Institute of Science, under the supervision of Prof. Doron Lancet and Prof. Ephraim Katchalski-Katzir. Thesis title: "Structural and evolutionary genomics of molecular recognition reper toires"

AWARDS AND HONORS

1998 Winner of the first prize in the national competition for multidisciplinary Ph.D. study. Awarded by the Dean of the faculty of Mathematics and Natural Sciences, The Hebrew University, Jerusalem.

2000 Prize of Distinction for outstanding Ph.D. studies at the Feinberg Graduate School, Weizmann Institute of Science.

SCHOLARSHIPS

1997 A Fellowship of Distinction for "outstanding achievement in studies and research", awarded the Dean of the Feinberg Graduate School, the Weizmann Institute of Science.

1997-1998 John F. Kennedy Memorial Fund Scholarship from the Feinberg Graduate School, the Weizmann Institute of Science.

1999 Fulbright post-doctoral award.

2002 Fellowship of the PhRMA Foundation Center for Excellence in Integration of Genomics and Informatics, at Harvard University

POSITIONS

1990-1992 Research Assistant, Department of Botany, Tel Aviv University, with Prof. Roni Aloni. Subject: Anatomy and physiology of root development.

1992-1993 Research Assistant, Department of Molecular Microbiology and Biotechnology, Tel Aviv University, with Dr. Daniel Segal. Subject: genetic analysis of Drosophila embryonic development.

1996-1999 Research Associate in the Center for the Study of Molecular Recognition headed by Prof. Ephraim Katchalsky-Katzir at the Weizmann Institute of Science. Subject: algorithms for protein docking.

1999-present Research fellow with Dr. George M. Church, Department of Genetics, and Lipper center for computational genetics, Harvard Medical School

2000 Consultant for Pfizer Inc., Cambridge, MA. Subject: Sequence, structure and function in G protein-coupled receptors.

TEACHING

1992-1993 Teaching Assistant in mathematics, in the course "Introduction to Differential and Integral Calculus", Tel Aviv University.

1996 Teaching Assistant in the course "Receptors and Recognition" at the Feinberg Graduate School, the Weizmann Institute of Science.

1998 Lecturer in the course "Computational Genomic and Bioinformatics" at the Feinberg Graduate School, the Weizmann Institute of Science.

1999 Teaching Assistant in the course "Programming for Bioinformatics and Internet" at the Feinberg Graduate School, the Weizmann Institute of Science.

2000 Lecturer in a workshop on: "The Matlab computing and programming environment", Harvard University.

INVITED LECTURES

1. Spontaneous emergence of order in small auto catalytic sets maintained far from equilibrium: Application of a Receptor Affinity Distribution (RAD) model. Annual meeting of the Israeli Society for the Study of the Origins of Life, Rehovot Israel, 1994

2. A cellular automaton model for self replication of mutually catalytic primordial chemical sets. European Conference of Artificial Life, Granada Spain, 1995

3. The hypervariable ligand binding site of the olfactory receptors: potential application to combinatorial library design. Akzo-Nobel/Pharma laboratories, the Netherlands, 1997

4. The functional site of olfactory receptor proteins. European Bioinformatic Institute, EMBL, Cambridge, UK, 1997.

5. Predicting the structure of the olfactory receptor proteins: a multi-sequence modeling approach. Annual meeting of the Israeli Institute of Biotechnology, Nof-Ginosar, Israel, 1998.

6. A sequence derived energy-like function for prediction of membrane protein structure: application to the olfactory receptors. Euro-conference on Protein Folding and Structure Prediction, Torino, Italy, 1998

7. The molecular basis of the sense of smell: a national competition for multidisciplinary Ph.D. theses, Hebrew University Jerusalem, Israel, 1998.

8. A sequence derived energy-like function for prediction of membrane protein structure. Protein Folding Group, Institute of advance studies, Hebrew University Jerusalem, Israel, 1999.

9. Computational analyses of the olfactory receptor repertoire. Senomyx Inc. La Jolla, 2001.

10. Computational identification of genetics regulatory networks. DIMACS Workshop on Integration of Diverse Biological Data, Piscataway, NJ. 2001.

11. Combinatorial analyses of promoter elements reveal the structur of genetics regulatory networks. Harvard Center for Genome Research, Cambridge, MA. 2001.

12. Computational analyses of gene regulatory networks. Department of Biology, MIT, MA. 2002