A global motif synergy map
motif orientation
The nodes in these graphs represent known or putative motifs and are indicated either by a filled black circle
or an oval containing the name of the motif. The names of putative motifs start with the letter "m" and
indicate the MIPS functional category from which they were derived mRPE-Ribosomal Protein Element,
mRRPE-rRNA Processing Element, mRRSE-rRNA Synthesis Element. "Motif name' " indicates a variant of the
motif found in the literature (same motif name without the symbol ') that was generated by running AlignACE
on the promoters of genes known to be regulated by the motif. The edges (lines) connect motif pairs that
significantly synergize in at least one of the seven expression experiments studied here and are colored
according to each expression condition in which the motif pair had a significantly high synergy score:
blue-heat shock, green-cell cycle, red-sporulation, purple-diauxic shift, black- pheromone, and orange-DNA
damage. Some motif names are marked according to the function of the genes they regulate or the MIPS functional
category from which they were derived: bold face-ribosomal proteins, italics-rRNA transcription/processing/synthesis,
underlined-cell cycle, shadow-amino acid biosynthesis-related.