General Flowchart

A. Strategy used to discover and analyze synergistic motif combinations. B.. Expression profiles of genes containing
the motifs for Mcm1 and/or SFF. In each panel, each grey line represents the normalized expression profiles of an
individual gene defined by the indicated motif/s during the cell cycle. The average expression profile of all
the genes displayed in the panel is shown in red. The expression coherence score (EC) for each group of genes is
also shown.