Resequencing analysis for Gene: POLR3B
There are 3 sections to this alignment: - resequencing alignment (unspliced, by construction) - Our alignments (spliced for coding sequence) - Alignments of ref. [1] (spliced for coding sequence) Note that: - these alignments should be taken in context with whole protein alignment. Spliced alignments may be interrupted by splicing events. - Putative signal of positive selection is shown in blue..... ....|1... ....|2... ....|3... ....|4... ....|5... ....|6... ....|7... ....|8... ....|9... ....|10.. ....|11.. ....|12.. ....|13.. ....|14.. ....| reseq__B2_humanF63 ------------------------------------------TTACCTGTGGCTATGATATTGA-GATGCTCTTGTTTTAAACAA-GGCCTCC-TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACACCA-AAGTTGCTTTTT-GC reseq__B2_humanF39 ------------TGGAC-AGTGATCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACTCCA-AAGTTGCTTTTT-GC reseq__B2_chimpF3 CACTACTCTAGCTGGAC-AGGAAGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACGCCA-AAGGTGCTTTTT-GC reseq__B2_chimpF27 ----------GCTGGACAGGGAAGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACGCCA-AAGGTGCTTTTT-GC reseq__B2_humanF27 ------------------------------------------TCGCTAGTGGCTATGATATTGA-GATGCTCTAGTTTTAAACAA-GGCCTCC-TTTCGACAGAAGGTAAGT-GAATTTTCAAAACTAACACCA-AAGTTGCTTTTT-GC reseq__B2_humanF51 ------------------------------------------ACCTAGGTGGCTATGATATTGA-GATGCTCTAGTTTTAAACAA-AGCCTCC-TTTCGACAGA-GGTAAGT-GAATTTTCAAAACTAACACCA-AAGTTGCTTTTT-GC reseq__B2_chimpF39 ------TCGAGCTGGAC-AGGGTGCAACACTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACGCCA-AAGGTGCTTTTT-GC reseq__B2_humanF87 ------------------------------------------TGACTAGTGGCTATGATATTGA-GATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACACCA-AAGTTGCTTTTT-GC reseq__B2_chimpF51 ------TCTAGCTGGAC-ACGATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACGCCA-AAGGTGCTTTTT-GC reseq__B2_chimpF87 -------TTAGCTGGACTAGGCAGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACGCCA-AAGGTGCTTTTT-GC reseq__B2_humanF15 -----------------------------------------------------AGCATATTGAA-GATGCTCTAGTTTTAAACAA-GGCCTC--TTTCGACAGA-GGTAAGT-GAATTTTCAAAACTAACACCA-AAGTTGCTTTTT-GC reseq__B2_humanF3 -------------------------------------------------------------------------GGTTTTAAACAAAGGCCTCCTTTTCGACAGAAGGTAAGTAGAATTCTCAAAACTAACACCA-AAGTTGCTTTTTCGC primer_B2 GAAACTGCCAGCTGGAC-AGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACNCCA-AAGNTGCTTTTT-GC reseq__B2_chimpF63 ------ATCTGCTGGACTAGGCA-CAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACGCCGGAAGGTGCTTTTT-GC reseq__B2_chimpF15 ------------TGGACAGGGAAGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACGCCA-AAGGTGCTTTTT-GC reseq__B2_humanF75 -------------------------------------------CTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACACCA-AAGTTGCTTTTT-GC reseq__B2_chimpF75 -------CATGCTGGAC-AGGATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGACAGA-GGTAAGT-GAATTTTCAAAACTAACGCCA-AAGGTGCTTTTT-GC # Our alignments (spliced for proteins) human_dna ----------------------------------------------TAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGAC----GGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTG chimp_dna ----------------------------------------------TAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAA-GGCCTC--TTTAGAC----GGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTG macaque_dna ----------------------------------------------TAGTGGCTATGATATTGAAGATGCCCTTGTTTTAAACAA-GGCCTC--TTTAGAC----GGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACATTG # Ref.[1] alignments (spliced for proteins) ENSP00000228347 ----------------------------------------------TAGTGGCTATGATATTGAAGATGCTCTT------AACAA-G----------AGA-----GGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTG ENSPTRP00000009150 ----------------------------------------------TAGTGGCTATGATATTGAAGATGCTCTT------AAGGC-C----------AGA-----GGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTG ENSMMUP00000006893 ----------------------------------------------TAGTGGCTATGATATTGAAGATGCCCTT------AACAA-G----------AGA-----GGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACATTG 15.. ....|16.. ....|17.. ....|18.. ....|19.. ....|20.. ....|21.. ....|22.. ....|23.. ....|24.. ....|25.. ....|26.. ....|27. reseq__B2_humanF63 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTTTTAAGTTATTTGAATTTTATGATATAGAAACAGGAGGTGGTTGGGTT-------------------- reseq__B2_humanF39 AGAATTAGATATAGGGATGATTAATGTAAAAATCT---CTTGGTTAA-TGTCAGTTATAAGGTTAAGTT------------------------------------------------------ reseq__B2_chimpF3 AGAATTAGATATAGGGATGATTAATGTAAAAATCCT--CTTGGTGAAATG------------------------------------------------------------------------- reseq__B2_chimpF27 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTTTTAAGTTATTGAATGA--------------------------------------------------- reseq__B2_humanF27 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTTTTAAGTTATTTGAATTTTATGATATAGAAACAGGAGGTGGTTGGGTTGTCATGTTGGCTAGA----- reseq__B2_humanF51 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTTTTAAGTTATTTGAATTTTATGATATAGAAACAGGAGGTGGTTGGGTTTGCATGTTGGCTCAAACCTC reseq__B2_chimpF39 AGAATTAGATATAGGGATGATTAATGTAAAATTCA---TTTGGTTAATGTCCAGTTATAATT------------------------------------------------------------- reseq__B2_humanF87 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTTTTAAGTTATTTGAATTTTATGATATAGAAACAGGAGGTGGTTGGGTTTGGATGTTGGC--------- reseq__B2_chimpF51 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTTTTAAGTTATTTGAATTTATATCTGAAC---------------------------------------- reseq__B2_chimpF87 AGAATTAGATATAGGGATGATTAATGGAAAGAATCGAACTTGGTGAAATGTCTGTTTTAAGTTATTGAATCGTATATCC-------------------------------------------- reseq__B2_humanF15 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTTTTAAGTTATTTGAATTTTATGATATAGAAACAGGAGGTGGTTGGGTTGGAATGTTGGCTAG------ reseq__B2_humanF3 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTTTTAAGTTATTTGAATTTTATGATATAGAAACAGGAGGTGGTTGGGTTGCAATGTTGGCTTGA----- primer_B2 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTC----------------------------------------------------------------------- reseq__B2_chimpF63 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTCTAAGTTATTTGAATTTATATCTGAAG----------------------------------------- reseq__B2_chimpF15 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTTTTAAGTTATTGAATTTATATCT--------------------------------------------- reseq__B2_humanF75 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTTTTAAGTTATTTGAATTTAGATTGACCAG--------------------------------------- reseq__B2_chimpF75 AGAATTAGATATAGGGATGATTAATGTAAAAATCA---CTTGGTTAA-TGTCAGTTTTAAGTTATTGAATTTATATCTGAAAG---------------------------------------- # Our alignments (spliced for proteins) human_dna AAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCT------------ chimp_dna AAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCT------------ macaque_dna AAACGATATACCAATCAGACTTTTGATAAAGTAATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCT------------ # Ref.[1] alignments (spliced for proteins) ENSP00000228347 AAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCA--------- ENSPTRP00000009150 AAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCA--------- ENSMMUP00000006893 AAACGATATACCAATCAGACTTTTGATAAAGTAATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCA---------