Reviews

1) Siegfried, E., Ambrosio, L. and Perrimon, N. (1990) Serine/threonine protein kinases in Drosophila. Trends in Genetics  6, 357-362.

2) Finkelstein, R. and Perrimon, N. (1991) The molecular genetics of head formation in Drosophila. Development 11, 899-914.

3) Perkins, L. A. and Perrimon, N. (1991) The molecular genetics of tail development in Drosophila melanogaster. In Vivo 5, 521-532.

4) Noll, E., Perkins, L. A., Mahowald, A. P. and Perrimon, N. (1993) Approaches to identify genes involved in Drosophila embryonic CNS development. Journal of Neurobiology 24, 701-722.

5) Perrimon, N. (1993) The torso receptor protein tyrosine kinase signaling pathway: An endless story. Cell 74, 219-222.

6) Lu, X., Perkins, L. A. and Perrimon, N. (1993) The Torso pathway in Drosophila: a model system to study receptor tyrosine kinase signal transduction. Development Suppl., 47-56.

7) van den Heuvel, M., Klingensmith, J., Perrimon, N. and Nusse, R. (1993) Cell patterning in the Drosophila segment: engrailed and wingless antigen distributions in segment polarity mutant embryos. Development Suppl, 105-114.

8) Perrimon, N. (1994) Signalling pathways initiated by receptor protein tyrosine kinases in Drosophila. Current Opinion in Cell Biology 6, 260-266.

9) Perrimon, N. (1994) The genetic basis of patterned baldness in Drosophila. Cell 76, 781-784.

10) Siegfried, E. and Perrimon, N. (1994) Drosophila Wingless: A paradigm for the function and mechanism of Wnt signaling. Bioessays 16, 195-404.

11) Perrimon, N. and Desplan, C. (1994) Signal transduction in the early Drosophila embryo: when genetics meets biochemistry. Trends in Biochemical Sciences 19, 509-513.

12) Duffy, J.B. and Perrimon, N. (1994) The Torso pathway in Drosophila: Lessons on receptor protein tyrosine kinase signaling and pattern formation. Dev. Biol. 166, 380-395. PDF

13) Perrimon, N. (1995). Hedgehog and beyond. Cell. 80, 517-520.

14) Perrimon, N., Lu, X., Hou, X.S., Hsu, J-C.,  Melnick, M. Chou, T.-B. and Perkins, L. A. (1995). Dissection of the Torso signal transduction pathway in Drosophila. Molecular Reproduction and Development. Mol. Reprod. Dev. 42, 515-522.

15) Duffy, J.B. and Perrimon, N. (1996) Recent advances in understanding signal transduction pathways in worms and flies. Curr. Opin. in Cell Biol. 8, 231-238.

16) Perrimon, N. (1996) Serpentine proteins slither in the Wingless and Hedgehog fields. Cell 86, 513-516. PDF

17) Bellaiche, Y and Perrimon, N. (1997). La voie de signalisation Wingless chez la Drosophile. Medecine Sciences 13, 165-174.

18) Perrimon, N. and Perkins, L. (1997). There must be 50 ways to rule the signal: the case of the Drosophila EGF receptor. Cell 89, 13-16. PDF

19) Engstrom, L., Noll, E. and Perrimon, N. (1997) Paradigms to study signal transduction pathways in Drosophila. Curr. Topics in Dev. Biology.  35, 229-261.

20) Mathey-Prevot, B. and Perrimon, N. (1998) Mammalian and Drosophila blood: JAK of all trades? Cell 92, 697-700. PDF

21) Perrimon, N. (1998) Creating Mosaics. IJDB.  42, 243-247. PDF

22) Perrimon, N. and Nusse, R.  (1998) Highlights of the 1998 Wnt Meeting. BBA. 1377, R45-R49.

23) Perrimon, N. (1998) Editorial. Methods.14, 353.

24) Perrimon, N. (1998) New advances in Drosophila provide opportunities to study gene functions. P.N.A.S.95, 9716-9717. PDF

25) Schulman, J.M., Perrimon, N. and Axelrod, J. (1998).  Frizzled Signaling and Developmental Control of Cell Polarity. TIG. 14, 452-458. PDF

26) Perrimon, N. and Duffy, J.(1998) Sending all the right signals, the case of the EGFR  Nature 396, 18-19. PDF

27) Perrimon, N. and McMahon, A. P. (1999) Negative feedback loops and their roles during pattern formation. Cell 97, 13-16. PDF

28) Spana, E. and Perrimon, N. (1999) The latest in Signal Transduction. TIG. 15, 301-302. PDF

29) Perrimon, N. and Stern, C. (1999) Pattern Formation and Developmental mechanisms. Editorial Overview. Current Opinion in Genetics and Development 9, 387-389.

30) Stronach, E. and Perrimon, N. (1999) Stress signaling in Drosophila. Oncogene 18, 6172-6182. PDF

31) Bellaiche, Y., The, I. and Perrimon, N. (2000) Role des proteoglycanes dans la distribution du facteur secrete Hedgehog. Medecine Sciences 2, 250-252.

32) Perrimon, N. and Bernfield, M. (2000) Specificities of Heparan Sulphate Proteoglycans in developmental processes. Nature  404, 725-728. PDF

33) Boutros, M. and Perrimon, N. (2000) Drosophila genome takes flight. Nature Cell Biology. 2, E53-E54. PDF

34) The, I. and Perrimon, N. (2000) Morphogen diffusion: The case of the Wingless protein.  Nature Cell Biology. 2, E79-E82. PDF

35) Zeidler, M. P., Bach, E. A. and Perrimon, N. (2000) The roles of the Drosophila JAK/STAT pathway. Oncogene  19, 2598-2606. PDF

36) Zeidler, M. P. and Perrimon, N. (2000) Sex Determination: Co-opted signals  determine gender. Current Biology 10, R682-R684. PDF

37) Lin, X. and Perrimon, N. (2000) Role of heparan  sulfate proteoglycans  in cell-cell- signaling in Drosophila.  Matrix Biology. 19, 303-307.

38) Noselli, S. and Perrimon, N. (2000) Are there close encounters between signaling pathways? Science. 290, 68-69.

39) Baeg, G. H. and Perrimon, N. (2000) Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila. Current Opinion in Cell Biology 12, 575-580. PDF

40) Perrimon, N. and Bernfield, M. (2001) Cellular Functions of Proteoglycans- an overview. Seminars in Cell and Development Biology 12, 1-3. PDF

41) Boutros, M. and Perrimon, N. (2001) Drosophila Wnt/Fz pathways. Sci STKE. 2005 May 10;2005(283):cm5.

42) Vincent, S. and Perrimon, N. (2001) Fishing for Morphogens. Nature 411, 533-536. PDF

43) Selva, E. and Perrimon, N. (2001) Role of Heparan Sulfate Proteoglycans in Cell Signaling and Cancer.  Advances in Cancer Research. 83, 67-80. PDF

44) Vincent, S., Perkins, L.A.P. and Perrimon, N. (2001). Doublesex surprises. Cell 106, 399-402. PDF

45) Moon, R .T., Bowerman, N., Boutros, M. and Perrimon, N. (2002) The promise and perils of Wnt signaling through ß-catenin. Science 296, 1644-1646. PDF

46) Schöck, F., and Perrimon, N. (2002) Molecular mechanisms of epithelial morphogenesis. Annual Review of Cell and Developmental Biology 18, 463-493. PDF

47) Nybakken, K. and Perrimon, N. (2002) Hedgehog signal transduction: recent findings. Current Opinion in Genetics and Development 12, 503-511. PDF

48) Schober, M. and Perrimon, N. (2002) Unconventional ways to travel. Nature Cell Biology.  4. E211-212. PDF

49) Nybakken, K. and Perrimon, N. (2002) Heparan Sulfate Proteoglycan modulation of Developmental Signaling in Drosophila. Biochimica and Biophysica Acta. 1573, 280-291. PDF

50) Hou, S.X., Zheng,Z. Chen, X. and Perrimon, N. (2002) The JAK/STAT Pathway in model organisms: Emerging roles in cell movement. Developmental Cell 3, 765-778. PDF

51) Lin, X. and Perrimon, N. (2002) Developmental Roles of Heparan Sulfate Proteoglycans in Drosophila. Glycoconjugate Journal. 19, 363-368. PDF

52) Nagy, A., Perrimon. N., Sandmeyer, S. and Plasterk, R, (2003) Tailoring the genome: the power of genetic approaches. Nature Genetics 33 Supplement: 276-84. PDF

53) Gibson, M. and Perrimon, N. (2003) Apico-basal Polarity: Epithelial form and function. Current Opinion in Cell Biology 15, 747-752. PDF

54) Perkins, L. A. P. and Perrimon, N. (2003) Liz and Norbert at the movies. Development 130, 5556-5557.

55) Agaisse, H. and Perrimon, N. (2004) The roles of JAK/STAT Signaling in Drosophila Immune Response. Immunological Reviews 198, 72-82. PDF

56) Perrimon N., and Hacker U. (2004) Wingless, Hedgehog and Heparan Sulfate Proteoglycans. Development. 131, 2509-2511. PDF

57) Perrimon N. (2004) Le modèle américain. Commentaire 106, 335-338.

58) Friedman A. and Perrimon N. (2004) Genome-wide high-throughput screens in functional genomics. Current Opinion in Genetics and Development. Curr Opin Genet Dev.14:470-6. PDF

59) Dasgupta R. and Perrimon N. (2004) Using RNAi to catch Drosophila genes in a web of interactions: Insights into Cancer research. Oncogene. 23, 8359-65. PDF

60) Armknecht S., Boutros M., Kige, K., Nybakken K., Mathey-Prevot, B. and Perrimon, N. (2005) High-throughput RNAi screens in Drosophila tissue culture cells. Methods in Enzymology. 392:55-73. PDF

61) Dasgupta R., Boutros M. and Perrimon N. (2005) Drosophila Wnt/Fz pathways. Science's STKE Connections Map. http://stke.sciencemag.org/cgi/cm/CMP 6559.

62) Haecke, U., Nybakken K. and Perrimon, N. (2005) Heparan Sulfate Proteoglycans: The sweet side of Morphogens. Nature Review in Molecular Cell Biology. 6, 530-541. PDF

63) Kulkarni M. and Perrimon N. (2005) Super-Size Flies. Cell Metabolism. 1 1-2. PDF

64) Echeverri C. and Perrimon N. (2006) High-throughput RNAi screening in cultured cells: a user's guide. Nature Reviews Genetics. 7, 373-384. PDF

65) Friedman A. and Perrimon N. (2006) High-throughput approaches to dissecting MAPK signaling pathways. Methods. 40, 262-71 PDF

66) Echeverri C. J., Beachy P. A., Baum B., Boutros M., Buchholz F., Chanda S. K., Downward J., Ellenberge, J., Frase, A. G., Hacohen N., Hahn W.C., Jackson .AL., Kiger A., Linsle, P S., Lum L., Ma M., Mathey-Prévô, B., Root .DE., Sabatin, .DM., Taipale J., Perrimon N. and Bernards R. (2006) Minimizing the risk of reporting false positives in large-scale RNAi screens. Nature Methods 3. 777-779. PDF

67) Perrimon N., Friedman A., Mathey-Prevot B. and Eggert U.S. (2007) Drug-target identification in Drosophila cells: Combining high-throughout RNAi and small molecules screens. Drug Discovery Today 12, 28-33. PDF

68) Perrimon N. and Mathey-Prevot B. (2007) Matter Arising: Off-targets and genome-scale RNAi screens in Drosophila. FLY 1, 1-5 PDF

69) Perrimon N. and Mathey-Prevot B. (2007) Applications of High-throughput RNAi Screens to Problems in Cell and Developmental Biology. Genetics 175, 7-16. PDF

70) Friedman A. and Perrimon N. (2007) Genetic screening for signal transduction in the era of network biology. Cell 128, 225-231 PDF

71) Mathey-Prevot B. and Perrimon N. (2007) Do-it-yourself RNAi made easy? Nature Methods 4, 308-9 PDF

72) Ramadan N., Flockhart I., Booker M., Perrimon, N. and Mathey-Prevot, B. (2007) Design and implementation of high throughput RNAi screens in cultured Drosophila cells. Nature Protocols 2, 2245-64. PDF

73) Leopold P. and Perrimon N. (2007) Drosophila and the genetics of the internal milieu. Nature 450, 186-188 PDF

74) Pitsouli C. and Perrimon N. (2008). Our fly cousins' gut. Nature. 454, 592-593. PDF **

75) Vinegon C., Razansky D., Pitsouli C., Perrimon N., Ntziachristos, V., Weissleder, R. (2009) Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. J Vis Exp. (30). pii: 1510. doi: 10.3791/1510.

76) Bai J., Sepp K.J., Perrimon N. (2009) Culture of Drosophila primary cells dissociated from gastrula embryos and their use in RNAi screening. Nat Protoc. 4(10)1502-12. PDF

77) Pitsouli C., Apidianakis Y., Perrimon N. (2009) Homeostatis in infected epithelia: stem cells take the lead. Cell Host & Microbe. 6(4): 301-7 PDF***

78) Mohr S., Bakal C., Perrimon N. (2010) Genomic Screening with RNAi: Results and Challenges. Annu. Rev. Biochem. 2010. 79:37–64. PMCID: PMC3564595. PDF

79) Bakal C. and Perrimon N. (2010) Realizing the promise of RNAi highthroughput screening. Developmental Cell. 18, 506-507. PMCID: PMC2868582. PDF***

80) Rajan A. and Perrimon N. (2010) Steroids make you bigger? Fat chance says Myc. Cell Metabolism. 12, 7-9. PDF***

81) Karpowicz P. and Perrimon N. (2010) All for one, and one for all: the clonality of the intestinal stem cell niche. F1000 Report. 2:73. PMCID: PMC298962. PDF*

82) Zirin J. and Perrimon N. (2010) Drosophila as a model system to study autophagy. Seminars in Immunopathology. 32(4):363-72. PMCID: PMC3562086. PDF*

83) Neumüller R.A. and Perrimon N. (2010) Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila. WIREs SysBioMed. 3(4):471-8. PMCID: PMC3560415. PDF*

84) Rajan A. and Perrimon N. (2011) Drosophila as a model for interorgan communication: lessons from studies on energy homeostasis. Dev. Cell. 21(1):29-31. PMCID: PMC3560414. PDF**   

85) Perrimon N. and Barkai N. (2011) The era of Systems Developmental Biology. Current Opinion in Genetics & Development. 21: 681-683. PMID: 22079435. PDF   

86) Mohr S. and Perrimon N. (2012) RNAi screening: New approaches, understandings and organisms. Wiley Interdiscip Rev RNA. 3(2):145-58. PMCID: PMC3249004. PDF   

87) Rajan A. and Perrimon N. (2013) Of flies and men: insights on organismal metabolism from fruit flies. BMC Biology. doi: 10.1186/1741-7007-11-38. PMCID: PMC3626883. PDF   

88) Zhou R., Mohr, S., Hannon G.J. and Perrimon N. (2013) Inducing RNAi in Drosophila cells by transfection with dsRNA. Cold Spring Harb Protoc. 2013(5). pii: pdb.prot074351. doi: 10.1101/pdb.prot074351. PMID:23637371. PDF   

89) Demontis, F., Piccirillo, R., Goldberg, A. L. and Perrimon, N. (2013) The influence of skeletal muscle on systemic aging and lifespan. Aging cell. doi: 10.1111/acel.12126. PMID:23802635. PDF

90) Tipping, M. and Perrimon, P. (2013) Drosophila as a model for context-dependent tumorigenesis. J. Cell Physiology. doi: 10.1002/jcp.24427. PMID: 23836429. PDF

91) Piccirillo, R., Demontis, F., Perrimon, N., and Goldberg, A. L. (2013) Mechanisms of Muscle Growth and Atrophy in Drosophila and Mammals. Dev Dyn. doi: 10.1002/dvdy.24036. PMID: 24038488. PDF

92) Demontis, F., Piccirillo, R., Goldberg, A. L. and Perrimon, N. (2013) Mechanisms of skeletal muscle aging: insights from mammals and Drosophila. Disease Models and Mechanisms. 6, 1339-52. PMCID: PMC3820258. PDF

93) Droujinine, I. A. and Perrimon, N. (2013) Defining the interorgan communication network: Systemic coordination of organismal cellular processes under homeostasis and localized stress. Front. Cell. Infect. Microbiol. 3:82. doi: 10.3389/fcimb.2013.00082. PDF

94) Owusu-Ansah, E. and Perrimon, N. (2014) Modeling metabolic homeostasis and nutrient sensing in Drosophila: implications for aging and metabolic diseases. Disease Models and Mechanisms. 7:343-50. PMCID: PMC3944494. PDF *

95) Mohr, S. E., Hu, Y., Kim, K. Housden, B.E. and Perrimon, N. (2014) Resources for functional genomics studies in Drosophila melanogaster. Genetics. May;197(1):1-18. doi: 10.1534/genetics.113.154344. Epub 2014 Mar 20. PMID:24653003. PMCID: PMC4012471. PDF **

96) Doupe, D. P. and Perrimon, N. (2014) Visualizing and manipulating temporal signaling dynamics with fluorescence-based tools. Sci. Signal. 1;7(319):re1. doi: 10.1126/scisignal.2005077. PMID: 24692594. PDF **

97) Zhou, R., Mohr, S., Hannon, G. J. and Perrimon, N. (2013) Inducing RNAi in Drosophila cells by soaking with dsRNA. Cold Spring Harb Protoc. 2014(5). pii: pdb.prot080747. doi: 10.1101/pdb.prot080747. PMID: 24786505. PDF

98) Mohr, S. E., Smith, J. A., Shamu, C. E., Neumuller, R. A. and Perrimon, N. (2014) RNAi screening comes of age: improved techniques and complementary approaches. Nature Review in Molecular and Cellular Biology. Sep;15(9):591-600. doi: 10.1038/nrm3860. PMID: 25145850. PMCID: PMC4204798. PDF

99) Housden, B. E. and Perrimon, N. (2014) Spatial and temporal organization of signaling pathways. Trends in Biochemical Sciences. Oct;39(10):457-464. doi: 10.1016/j.tibs.2014.07.008. Epub 2014 Aug 22. PMID: 25155749. PDF

100)Droujinine I.A., Yan D., Perrimon N. (2014) A sharp end to sugary Wingless travels. J Cell Biol. 2014 Sep 29;206(7):819-821. PMID:25267292. PMCID: PMC4178964. PDF

101) Housden, B. E., Lin. S. and Perrimon, N. (2014) Cas9-based genome editing in Drosophila. Methods in Enzymology. 546:415-39. doi: 10.1016/B978-0-12-801185-0.00019-2. PMID: 25398351. PDF

102) Owusu-Ansah, E. and Perrimon, N. (2015) Stress Signaling Between Organs in Metazoa. Annual Review in Cell and Developmental Biology. PMID: 26393775 PDF

103) Sopko R., and Perrimon N., Systematic Methods to Interrogate Genetic Perturbations and Map Phosphorylation- Dependent Signaling. In: Ralph A Bradshaw and Philip D Stahl (Editors-in-Chief), Encyclopedia of Cell Biology, Vol 4, Waltham, MA: Academic Press, 2016, pp. 227-233. PDF

104) Doupe D., and Perrimon N., Toward a Systems Understanding of Signaling Pathway Function. In: Paul M. Wassarman, editor, Current Topics in Developmental Biology, Vol. 117, Burlington: Academic Press, 2016, pp. 221-236. PDF

* Open Access

** Open Access after 6 months

*** Open Access after 12 months