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I'm currently a postdoctoral fellow in George Church's lab in the Department of Genetics at Harvard Medical School, where I have been developing quantitative microarray technologies and integrating a large-scale mutant phenotype analysis with computational modeling. Prior to this, I was a graduate student in Fred Winston's lab, using yeast genetics and molecular biology to study the mechanisms by which the SAGA complex regulates transcription. As genomic studies transition from technology development and proof of principle to more in-depth analyses of fundamental biological questions, the integration of conventional and genomic methods will become even more important. I plan to apply this type of systems biology approach to elucidate connections between key cellular pathways, focusing initially on mitochondrial function and the mitotic cell cycle in S. cerevisiae. For more information, see my:
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